Today I bring a scientific articles related to a fish often hold in our tanks. The famous and well-known zebrafish.
The embryonic development of zebrafish (Danio rerio ) was filmed in a high-resolution video without disrupting the fragile process. Zebrafish danio rerio or a cyprinid related to carp and catfish, native to Southeast Asia , often used in aquariums as well as scientific research.
Researchers Madrid Polytechnic University have developed a new technique to visualize and quantify the embryonic development of zebrafish (Danio rerio ). The research is published in the journal Science and describes the development from the first fertilized cell to its conversion into an embryo of 1000 cells in three hours. All this with unprecedented precision. Here you can see the video in question.
Scientists propose a new method to shoot the early stages of development and build the cell lineage tree. It involves identifying the position of each cell from the embryo.
To carry out this method we have developed a microscopy technique that generates a 3D image of the embryo alive every minute taking advantage of the nonlinear optical properties of the membranes and cell nuclei. All this is done by mathematical algorithms applied to images obtained are digitally reconstruct get all the cells of the embryo and measure characteristics such as the shape of the cell membrane.
has been shown that the processes that occur during this stage of development are more asynchronous and asymmetric than previously thought. The first divisions in the embryo are not synchronous but occur in a pattern as a wave (or wave) through the embryo. This causes the cells arising from the same division do not divide at the same time.
The proposed methodology will serve as reference for future studies in systems biology. Explains Miguel A. Luengo-Oroz - coauthor of the publication, "the collaboration between biologists, engineers, mathematicians and physicists This research is a clear example of how biology is entering the digital age. Multidisciplinary research teams will be increasingly important in biomedical research in the coming years.
turns out that this fish is starting to replace the rats in the experimental laboratories. The reason is that, besides being one of the easiest to breed in an aquarium, has a number of advantages compared to other vertebrates. Among them is that their development occurs outside the mother's body in the water, and the embryos are transparent, allowing you to see the changes that occur as the minnows are taking shape.
Another advantage is that you can see the effects of various drugs and toxic substances on your internal organs.
One day after fertilization have already formed the segmentation of the brain, the neural tube, precursor of the Central Nervous System, and the somites, which give rise to muscles and bones. Five days have been trained eyes and ears and shows the heart, liver, kidneys and pancreas. And the circulatory, digestive and nervous systems are in operation.
These characteristics have made that before was nothing but a pet has been cast in the laboratory as a young talent capable of shedding light on diseases such as cancer and Parkinson's. Although the list of diseases where it is "working" includes other disorders as diverse as the immune system, cardiovascular, sleep disorders or drug dependence.
What do you think? Do you agree that you experiment with them for our benefit? Well, today I hope you've learned a lesson about the importance of aquariums, which increasingly goes further. Greetings to all readers.
0 comments:
Post a Comment